Detection and Kinetics of Subgenomic Severe Acute Respiratory Syndrome Coronavirus 2 RNA Viral Load in Longitudinal Diagnostic RNA-Positive SamplesArticle Published on 2022-09-132022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] Above acute respiratory syndrome characterized collected coronavirus coronavirus 2 COVID-19 detectable detection diagnostic duration of illness identify independent Kinetics large sample linear load longitudinal nasal swab nucleic acid amplification participant peaking polymerase chain Postexposure Prophylaxis replicating virus Replication respiratory RNA RT-PCR Sample SARS-CoV-2 sgRNA sgRNAs subgenomic RNA swab sample Symptom threshold trajectory Treatment Viral load Viral load. viral replication Viral RNA while [DOI] 10.1093/infdis/jiac048 PMC 바로가기
Retinal microvascular morphology versus COVID-19: What to anticipate?Research article Published on 2022-09-012022-10-05 Journal: Photodiagnosis and photodynamic therapy [Category] COVID19(2023년), SARS, 바이오마커, 변종, [키워드] age angiotensin-converting enzyme 2 complete recovery COVID-19 COVID-19 infected patient COVID-19 infection cross-sectional Diagnosis eyes Foveal avascular zone group healthy subject healthy subjects Microvascular morphology morphological change morphology no significant difference Optical coherence tomography Optical coherence tomography angiography outer retina parameter parameters pathogenic mechanism patients positive recorded Region Result Retina Retinal SARS-COV-2 infection significant changes in significant difference significantly lower subjects swab sample thrombotic vessel Vessel density [DOI] 10.1016/j.pdpdt.2022.102920 [Article Type] Research article
Nano-treatment of HEPA filters in COVID-19 isolation rooms in an academic medical center in Saudi ArabiaResearch article Published on 2022-09-012022-10-05 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome aerosol-generating procedures airborne Antiviral cause coated collected Contamination coronavirus coronavirus disease COVID-19 COVID-19 patients detect diagnosed disease droplet Effectiveness Efficiency evaluated facilitate filtration First wave FIVE HEPA HEPA filter hospital intensive care investigated Isolation room material media outbreak pandemic Patient positive Result Sample SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission Saudi Arabia Silver-titanium nanoparticles Spread swab sample tested Transmission Treatment viability virus virus particles [DOI] 10.1016/j.jiph.2022.07.004 [Article Type] Research article
A rapid RT-LAMP SARS-CoV-2 screening assay for collapsing asymptomatic COVID-19 transmissionArticle Published on 2022-09-012022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, 치료제, [키워드] 48 hours assays Asymptomatic Asymptomatic COVID-19 clinically Collapsing diagnostic genomic individual Laboratory testing National NHS nine participant positive processed reducing reported RT-LAMP RT-PCR SARS-CoV-2 sensitivity sequence specificity subsequent supported swab sample Symptom Transmission transmission of SARS-CoV-2 Trust university utility validation was determined [DOI] 10.1371/journal.pone.0273912 PMC 바로가기
Identifying novel host-based diagnostic biomarker panels for COVID-19: a whole-blood/nasopharyngeal transcriptome meta-analysisCOVID-19에 대한 새로운 호스트 기반 진단 바이오마커 패널 식별: 전혈/비인두 전사체 메타 분석Meta-Analysis Published on 2022-08-032022-09-11 Journal: Molecular Medicine [Category] SARS, 바이오마커, 유전자 메커니즘, 치료기술, [키워드] Accuracy acute respiratory illness acute respiratory illnesses analysis applied ARI bioinformatics Biomarker Blood Cell cell cycle Characteristics Combination complementary controls COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patients COVID-19 sample cross cytokine cytokine production Data integration dataset Defense detect diagnose diagnostic diagnostic biomarker Diagnostic biomarkers Diseases eight enhancement feature gene expression profile Gene ontology HCs healthy control healthy controls Host host gene host response identifying Immune cell improvement Improvements independent indicated induce Infection Inflammatory interferon introduced lack machine learning algorithm Machine learning algorithms marker Meta-analysis nasopharyngeal Nasopharyngeal swab Ontology Pathogenesis pathway pathway enrichment patients with COVID-19 proportion Random forest respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis selected swab sample System Systems biology Transcriptome upregulation Viral virus Whole blood whole blood. [DOI] 10.1186/s10020-022-00513-5 PMC 바로가기 [Article Type] Meta-Analysis
Preparation of the luciferase-labeled antibody for improving the detection sensitivity of viral antigen바이러스 항원의 검출감도 향상을 위한 루시페라제 표지 항체의 제조Article Published on 2022-07-282022-09-11 Journal: Virology Journal [Category] COVID19(2023년), SARS, 치료기술, [키워드] antibody antigen detection antigens applied Automatic Automatic magnet chemiluminescence immune assay (AMCA) auxiliary chemiluminescence clinical evaluation clinical sensitivity detect detection antibody Detection sensitivity Diagnosis ELISA evaluated expected gold Highly sensitive HRP immune IMPROVE Improving inactivated labeled antibody labeling limit of detection luciferase monoclonal antibody nano luciferase nLuc pathogen PCR-negative PCR-positive peroxidase preparation produced reached reporter respiratory syndrome coronavirus respiratory syndrome coronavirus 2 SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 virus SARS-CoV-2. sensitivity significantly specificity Spike protein swab sample swab samples the SARS-CoV-2 Viral antigen viral infections viral spike protein virus virus antigens virus detection virus infection [DOI] 10.1186/s12985-022-01855-6 PMC 바로가기 [Article Type] Article
Detecting lineage-defining mutations in SARS-CoV-2 using colorimetric RT-LAMP without probes or additional primers프로브 또는 추가 프라이머 없이 비색 RT-LAMP를 사용하여 SARS-CoV-2에서 계통 정의 돌연변이 검출Article Published on 2022-07-072022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] advance alternatives approach caused concern country demonstrated develop epidemic wave Gamma Genetic variant help identify immune increasingly isothermal amplification lineages Loop-mediated isothermal amplification molecular monitoring Mutation nucleic acid nucleic acid amplification pandemic of COVID-19 primer probe proof proof of concept reaction RNA samples RT-LAMP SARS-CoV-2 SARS-CoV-2 RNA sensitivity sequencing coverage specificity sustained swab sample swab samples tested Transcription vaccination variant variants VoC whole-genome sequencing [DOI] 10.1038/s41598-022-15368-3 PMC 바로가기 [Article Type] Article
A Biosensor Platform for Point-of-Care SARS-CoV-2 Screening현장 진료 SARS-CoV-2 스크리닝을 위한 바이오센서 플랫폼Article Published on 2022-07-032022-09-11 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] agency biosensor calibrated can be used capacitance collected data condition correlation COVID-19 COVID-19 pandemic Economy effective Efficiency facilitated Health hospitalized patients individual inductance Interdigitated electrodes Internet Internet of Things Laboratory LCR less Liquid-crystal display measure offer pandemic Patient platform Portable professional public health readout Research SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 particles SARS-CoV-2 patients SARS-CoV-2 testing scientist Screening Smartphone Space Spike protein Spread swab sample swab samples test result virus virus detection virus monitoring. [DOI] 10.3390/bios12070487 PMC 바로가기 [Article Type] Article
Evaluation of Four Point of Care (POC) Antigen Assays for the Detection of the SARS-CoV-2 Variant OmicronSARS-CoV-2 변이체 오미크론 검출을 위한 4가지 진료 시점(POC) 항원 분석 평가Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] Abbott Analysis analytical sensitivity Antigen assays Asymptomatic average Cell culture contributing to correlated Cycle threshold value ddPCR Delta delta variant detect detectable detection diagnostics digital PCR Dilution discrepancies discrepancy Ensuring evaluated Genome highest Infectious virus infectious virus titer limit limit of detection LOD log manuscript molecular N gene omicron Omicron variant POC Point point of care point-of-care positive quantified Rapid antigen tests rapid antigen tests. Real-time PCR reduced replicate RNA SARS-CoV-2 specimen Spread swab sample symptomatic tested the SARS-CoV-2 vaccinated individuals variant variant of SARS-CoV-2 Viral viral stock viral stocks virus stock virus titer [DOI] 10.1128/spectrum.01025-22 PMC 바로가기 [Article Type] Article
ACE2 expression in saliva of patients with COVID-19 and its association with Candida albicans and Aggregatibacter actinomycetemcomitansArticle Published on 2022-05-232022-11-16 Journal: F1000Research [Category] COVID19(2023년), SARS, 치료기술, [키워드] ACE2 ACE2 expression ACE2 mRNA Actin Aggregatibacter actinomycetemcomitans ALS3 analysis angiotensin-converting enzyme 2 association Bacteria C. albican Candida Candida albican Candida albicans collected contribute control group controls correlation COVID-19 COVID-19 severity determine diabete evaluated expression Fusobacterium Fusobacterium nucleatum Genes groups healthy hospitalized patient hyphal Indonesia investigated involved mRNA expression no significant difference oral microbiota participant Patient patients patients with COVID-19 patients with diabete PCR-confirmed COVID-19 performed Prognosis proportion Protein protein 3 qPCR quantitative PCR Saliva SARS-COV-2 infection selected significantly higher subject susceptibility Swab swab sample the patient tongue Transcription Veillonella parvula. [DOI] 10.12688/f1000research.111965.2 PMC 바로가기